Not All Collagen is Created Equal - Why Collagen Induction Therapy Produces Natural Collagen NOT Scar Collagen
In any anti-aging situation , growth factors need to be stimulated by some means. Typically this is accomplished through controlled wounding. Several different types of growth factors are released according to the type of wound incurred. Growth factors are responsible for orchestrating and regulating cellular function and repair after injury. An ideal skin rejuvenation wounding or treatment would both improve the penetration of any active ingredient and wake up the fibroblast.
Unfortunately most rejuvenation treatments rely on dramatically invasive chemical peels, light or radio frequency to burn the skin, which leads to the release of TGF-B1 and TGF-B2 (transforming growth factors), TIMP-1, and Heat Shock Protein 47. These generate a fibrotic response that promotes scar collagen (thick, parallel oriented bundles.)
By contrast collagen induction therapy or dermal needling results in increased TGF-B, FGF-7 (keratinocyte growth factor), and EGF (epidermal growth factor)which promotes natural collagen, with scarless wound healing.
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In the early stages of wound healing the fibroblasts produce hyaluronic acid which helps stimulate cell renewal. In fact, one of the reasons fetal wound healing is scar-less is there is an abundance of hyaluronic acid. Studies have shown that hyaluronic acid applied topically during a wound dressing are associated with quicker healing and reduce scarring. Oral Glucosamine taken in adequate amounts during the first few days of surgery or trauma enhance hyaluronic acid production in the wound thus also promoting swifter healing with fewer complications related to scarring.
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